Monoamine transporters in human endometrium and decidua
نویسندگان
چکیده
منابع مشابه
Monoamine transporters in human endometrium and decidua.
BACKGROUND Monoamines play important roles in decidualization, implantation, immune modulation and inflammation. Furthermore, monoamines are potent vasoactive mediators that regulate blood flow and capillary permeability. Regulation of the uterine blood flow is important both during menstruation and pregnancy. Adequate monoamine concentrations are essential for a proper implantation and physiol...
متن کاملPlasma membrane and vesicular monoamine transporters in normal endometrium and early pregnancy decidua.
The uterus is innervated by adrenergic sympathetic fibres, and the endometrium has a capability for endogenous monoamine synthesis. Extracellular monoamine levels are regulated primarily through re-uptake by specific membrane-bound transporter proteins dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter (SERT). Intracellular storage of monoamines involves vesi...
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In human endometrium, cytokines and growth factors that vary periodically during the menstrual cycles have been suggested to play various roles in uterine function. In the present study, differential gene expression in human endometrium between the proliferative and the secretory phases was investigated by using a human cDNA expression array system. Human interleukin (IL)-15 was identified as a...
متن کاملThe functional morphology of the human endometrium and decidua.
The functional morphology of the human endometrium and decidua has been investigated with particular attention to all aspects of implantation and contraception. The postovulatory triad (of glandular epithelium), comprising subnuclear glycogen, giant mitochondria, and the NCS seems to be involved in both implantation and contraception and has been studied in detail. Initial stages of glycogen fo...
متن کاملGalectin fingerprinting in human endometrium and decidua during the menstrual cycle and in early gestation
The emerging functionality of the sugar code via cell surface glycans and endogenous lectins ascribes pertinent roles in cell physiology to the carbohydrate signals of cellular glycoconjugates. To initiate monitoring of endogenous lectins in human endometrium, we focused on a family of growth/adhesion-regulatory lectins, i.e. galectins. Comprehensive fingerprinting was performed on samples thro...
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ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2008
ISSN: 1355-4786,1460-2369
DOI: 10.1093/humupd/dmn048